Menu

Analyzing the Gut Microbiome

The Huttenhower Lab at the Harvard Chan Center for the Microbiome in Public Health focuses on understanding the function of microbial communities, particularly in humans. This involves using the microbiome to predict disease onset, progression, and outcomes, as well as developing methods to modify it for health and treatment, applicable to conditions like IBD, cancer, diabetes, arthritis, and infections.

A recent paper from the lab explores how changes in the gut microbiome are linked to different types of inflammatory arthritis, aiming to identify specific bacteria and metabolic pathways that might contribute to these diseases. 

Computers are needed to analyze the large amounts of data from the gut microbiome, as the researchers seek to identify patterns and connections between specific bacteria and different types of inflammatory arthritis, including using software to process and interpret the complex biological information.

The study found that certain types of bacteria in the gut are linked to different forms of inflammatory arthritis, suggesting that the gut microbiome plays a key role in these diseases. The researchers also identified specific metabolic pathways that might be involved, offering potential new targets for treatment.

The Huttenhower Lab
Department of Biostatistics, Harvard T.H. Chan School of Public Health

Research projects

A Future of Unmanned Aerial Vehicles
Yale Budget Lab
Volcanic Eruptions Impact on Stratospheric Chemistry & Ozone
The Rhode Island Coastal Hazards Analysis, Modeling, and Prediction System
Towards a Whole Brain Cellular Atlas
Tornado Path Detection
The Kempner Institute – Unlocking Intelligence
The Institute for Experiential AI
Taming the Energy Appetite of AI Models
Surface Behavior
Studying Highly Efficient Biological Solar Energy Systems
Software for Unreliable Quantum Computers
Simulating Large Biomolecular Assemblies
SEQer – Sequence Evaluation in Realtime
Revolutionizing Materials Design with Computational Modeling
Remote Sensing of Earth Systems
QuEra at the MGHPCC
Quantum Computing in Renewable Energy Development
Pulling Back the Quantum Curtain on ‘Weyl Fermions’
New Insights on Binary Black Holes
NeuraChip
Network Attached FPGAs in the OCT
Monte Carlo eXtreme (MCX) – a Physically-Accurate Photon Simulator
Modeling Hydrogels and Elastomers
Modeling Breast Cancer Spread
Measuring Neutrino Mass
Investigating Mantle Flow Through Analyses of Earthquake Wave Propagation
Impact of Marine Heatwaves on Coral Diversity
IceCube: Hunting Neutrinos
Genome Forecasting
Global Consequences of Warming-Induced Arctic River Changes
Fuzzing the Linux Kernel
Exact Gravitational Lensing by Rotating Black Holes
Evolution of Viral Infectious Disease
Evaluating Health Benefits of Stricter US Air Quality Standards
Ephemeral Stream Water Contributions to US Drainage Networks
Energy Transport and Ultrafast Spectroscopy Lab
Electron Heating in Kinetic-Alfvén-Wave Turbulence
Discovering Evolution’s Master Switches
Dexterous Robotic Hands
Developing Advanced Materials for a Sustainable Energy Future
Detecting Protein Concentrations in Assays
Denser Environments Cultivate Larger Galaxies
Deciphering Alzheimer’s Disease
Dancing Frog Genomes
Cyber-Physical Communication Network Security
Avoiding Smash Hits
Analyzing the Gut Microbiome
Adaptive Deep Learning Systems Towards Edge Intelligence
Accelerating Rendering Power
ACAS X: A Family of Next-Generation Collision Avoidance Systems
Neurocognition at the Wu Tsai Institute, Yale
Computational Modeling of Biological Systems
Computational Molecular Ecology
Social Capital and Economic Mobility
All Research Projects

Collaborative projects

ALL Collaborative PROJECTS

Outreach & Education Projects

See ALL Scholarships
100 Bigelow Street, Holyoke, MA 01040