Welcome to the MGHPCC Virtual Booth

Yale University

Supporting Data-intensive Social Science

Yale's DISSC simplifies big data research by automating pipelines, enabling secure access, and optimizing massive datasets so researchers can focus on discovery, not infrastructure.

The Data-Intensive Social Science Center (DISSC) serves as a hub for social scientists at Yale who work with big data and secure datasets. The center provides support throughout the research lifecycle—assisting researchers in identifying appropriate data sources, establishing secure computing environments, and navigating applications for restricted data access.

A core aspect of DISSC’s mission is to ensure that large datasets are structured in ways that enable researchers to work with them efficiently. One notable example is the L2 voter database, which arrives as over 7 terabytes of raw data.

DISSC collaborated with the Yale Center for Research Computing (YCRC) to develop automated Nextflow pipelines that transform this massive raw dataset into optimized columnar formats, significantly improving query performance. Additionally, an Apache Spark cluster was implemented to allow horizontal scaling of processing power, which is essential when handling datasets of this magnitude.

In another pilot initiative, DISSC explored cloud-based querying for large-scale datasets. Working again with YCRC, the team established an ODBC connection that enables researchers to run queries against cloud-hosted datasets and retrieve results for local analysis at YCRC.

DISSC’s overarching goal is clear: to allow researchers to concentrate on their research rather than on the complexities of data infrastructure.

Yale Center for Research Computing

Principal Members

Yale

Featured Projects

A complicated future for a methane-cleansing molecule (working title)
SC25 Project
A Safer Way to See Inside Cells
Adaptive Deep Learning Systems Towards Edge Intelligence
SC25 Project
AI for Cancer Diagnosis
SC25 Project
AI Pareidolia
SC25 Project
AI That Speaks Human About Health
Ancient DNA reveals pervasive directional selection across West Eurasia (working title)
Bayesian Deep Gaussian Processes for Correlated Functional Data (working title)
SC25 Project
Better Pathogen Targeting
Research Computing Center
BU Research Computing Services
SC25 Project
Building for Floods
Campus Research Computing Consortium
Cellular Protein Electrochemical Balance (working title)
Combining AI with laboratory evolution yields improved proteins (working title)
Computation + Machine Intelligence | Wu Tsai Institute
Computational Modeling of Biological Systems
Computer Simulatioons Show Strong Ocean Currents Reduce Size of Surface Waves (working title)
SC25 Project
Computing Hidden Health Threats from Heat
Contribution of Task-Irrelevant Stimuli to Drift of Neural Representations (working title)
Deciphering Alzheimer's Disease
Developing Advanced Materials for a Sustainable Energy Future
Earth & Planetary Sciences at Harvard University
MGHPCC Project
Ecosystem for Research Networking
Efficient cooling method could enable chip-based trapped-ion quantum computers (working title)
Energy Science Network
MGHPCC Project
Expanding Computing Education Pathways (ECEP) Alliance
FABRIC Testbed
SC25 Project
FlowER: AI for Predicting Chemical Reactions
SC25 Project
Grid Responsive Data Centers
Research Computing Center
Harvard FASRC
IceCube: Hunting Neutrinos
Identifying non-coding variant effects at scale via machine learning models of cis-regulatory reporter assays (working title)
IEEE High Performance Extreme Computing Conference
Impact of Marine Heatwaves on Coral Diversity
Impulse response functions as a framework for quantifying ocean-based carbon dioxide removal (working title)
Internet2
Research Computing Center
Lincoln Laboratory Supercomputing Center (LLSC)
SC25 Project MGHPCC Project
Massachusetts AI Hub
SC25 Project MGHPCC Project
MGHPCC AI Computing Resource (AICR)
MGHPCC Supercloud
SC25 Project
Microplastic-Free by Design
MIT chemists design impact-resistant plastics (working title)
Research Computing Center
MIT Office of Research Computing and Data
SC25 Project
Multifunctional 3D-Printed Materials
MGHPCC Project
National Data Platform
SC25 Project
Naval and Ocean Renewable Energy Hydrodynamics
Research Computing Center
NEU Research Computing
New MetaMaterials Take Inspiration from Deep Sea Sponges (working title)
Northeast Research and Education Network
MGHPCC Project
Northeast Storage Exchange
Northern Crossroads
Novel study at URI seeks to treat neurological symptoms of rare genetic disorder (working title)
Open Cloud Testbed
ORCD Seed Fund
SC25 Project MGHPCC Project
OSN - Open Storage Network
Planning, Reminders and Micro-Incentives to Walk After Traumatic Brain Injury: A Pilot Randomized Control Trial (working title)
MGHPCC Project
PNRP- protype national research platform
Researchers develop molecular editing tool to relocate alcohol groups (working title)
Revolutionizing Materials Design with Computational Modeling
SC25 Project
Sailing the Symbiosis Seascape
Shear-Induced Structural Convergence but Formation-History-Dependent Yielding in Sequentially Gelled Binary Colloidal Networks (working title)
SC25 Project
Shining a Light on Dark Matter
Simulating Large Biomolecular Assemblies
Single-molecule tracker illuminates workings of cancer-related proteins (working title)
Software for Unreliable Quantum Computers
SC25 Project
Staving off the Banana Apocalypse
SC25 Project
Supporting Data-intensive Social Science
The Kempner Institute - Unlocking Intelligence
The US ATLAS Northeast Tier 2 Center
This AI scientist can run an X-ray experiment. Self-driving labs may come next (working title)
SC25 Project
Tracking Environmental Health Risks
Research Computing Center
UMass - URI Unity Cluster
Research Computing Center
UMass Amherst Research Computing and Data
Unity HPC and AI Platform
Research Computing Center
URI Institute for AI & Computational Research
SC25 Project
Wrangle Range Modeling
Yale Budget Lab
Yale Center for Genome Analysis (YCGA)
Research Computing Center
Yale Center for Research Computing
Yale Department of Earth and Planetary Sciences
Zebrafish Reveal New Insights into Biology of Autism (working title)
100 Bigelow Street, Holyoke, MA 01040